Significant variability and controversy exist in the post-operative management of patients undergoing major spinal instrumented surgeries. While surgeons have preferences in the management of their patients, little consensus exists in relation to the timing and type of antibiotic use, dressing type and duration, use of drains, and return to regular and more advanced activities. In this SRS webinar, in partnership with AO Spine, we will review the literature related to post-operative care of spinal deformity patients and highlight current trends of practice and areas of controversy that may be amenable to future study.